Signal Transduction
Q1. With the aid of a diagram describe the process whereby V. cholerae infects humans and disrupts signal transduction pathways. Terms that should be mentioned include: GPCR, G protein, adenylate cyclase, cAMP, ADP-ribosyl transferase. (15 marks)
Q2. With the aid of a diagram describe the process whereby Bordetella pertussis infects humans and disrupts signal transduction pathways. Terms that should be mentioned include: GPCR, G protein, adenylate cyclase, cAMP, ADP-ribosyl transferase. (15 marks)
Q3. Describe in detail how the V. cholerae toxic differs in its action from the Bordetella pertussis toxin