Signal Transduction

Q1. With the aid of a diagram describe the process whereby V. cholerae infects humans and disrupts signal transduction pathways. Terms that should be mentioned include: GPCR, G protein, adenylate cyclase, cAMP, ADP-ribosyl transferase. (15 marks)

Q2. With the aid of a diagram describe the process whereby Bordetella pertussis infects humans and disrupts signal transduction pathways. Terms that should be mentioned include: GPCR, G protein, adenylate cyclase, cAMP, ADP-ribosyl transferase. (15 marks)

Q3. Describe in detail how the V. cholerae toxic differs in its action from the Bordetella pertussis toxin

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