1. Sewall Wright first developed the method for
calculating inbreeding coefficients from
pedigrees in the early 1920’s. This is a small
part of his large pedigree for “The Duchess
family of Shorthorns as bred by Thomas Bates”.
This breed of cattle was developed in 1700’s1800’s by many generations of inbreeding and
artificial selection. Apparently, Favourite was a
favorite for breeding.
Which path diagram matches the pedigree of
Belvidere? (Hint: note that Belvidere’s parents
are full siblings.)

2. Over time, natural selection can cause populations to lose variation if less fit alleles are eliminated.
You suspect that natural selection has reduce variation in the global population of flu viruses during
the 2004 flu season. The easiest way to see if genetic variation was lost is to see how _____ changes
throughout the flu season

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